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The reason for this is that MIXTURE and Bayesian Lasso utilize linkage disequilibrium more efficiently.
Second, low genetic relatedness between reference animals and validation animals appears to favour mixture-distribution models [ 14], presumably because mixture-distribution models utilize linkage disequilibrium more efficiently than normal and thick tailed distribution models.
Second, we considered only one breed, in which the genotyped animals were closely related, implying that Bayesian Lasso and MIXTURE, which utilize linkage disequilibrium more efficiently, have no advantage over GBLUP [ 9, 14].
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Initial attempts to understand ASD genetics utilized linkage studies with most cohorts consisting of multiplex nuclear families.
Highly accurate genotypes are critical for detecting IBD, and BeagleCall utilizes linkage disequilibrium information to significantly improve the genotype accuracy.
Furthermore, we utilized linkage analysis to map QTL on Chr 14 in progeny from a cross between the CSS and host B6 strain.
This approach consists of predicting breeding values on the basis of a larger number of SNPs [ 9- 11], utilizing linkage disequilibrium (LD) between SNPs and the QTL.
Association mapping utilizes linkage disequilibrium (LD) to discover marker/trait associations for a set of diverse germplasm or sets of inbred lines resulting from multiple crosses (Zhu et al. 2008).
The PHASE software [ 51] and the locally developed CRIHAP package were applied to utilize both linkage and LD information for determining haplotypes and impute missing genotypes.
However, as the mean distance between two neighboring variants is longer than the length of the simulated sequence reads and the variant calling algorithms currently do not utilize reference linkage information, this limitation does not affect the results.
GO was immobilized on to 316L SS utilizing amide linkage, to generate a strongly adherent uniform coating with surface roughness.
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