Sentence examples for utilization of alternate from inspiring English sources

Utilization of alternate signaling pathways, in particular, heterodimerization of HER family members, is often responsible for de novo and acquired resistance to HER-targeted therapies [22], [23].

Fetal growth restriction compromises growth of nutrient storage organs such as adipose tissue and this is compensated by adaptive metabolic changes such as greater insulin sensitivity to favour energy efficiency and utilization of alternate source of substrates.

The results revealed that the high-affinity reductive Fe uptake system is required for the utilization of alternate carbon sources and for growth under both in vitro Fe-limiting and in vivo conditions.

The protein structure was corrected by the utilization of alternate conformations and valence monitor options as some crystallographic disorders as well as some unfilled valance atoms were present in the protein file.

Other mechanisms of endocrine resistance, largely based on cell lines and cell line xenografts, include the utilization of alternate signaling pathways (such as PI3K/AKT/mTOR or human epidermal growth factor B2 receptor/HER2), increased AP1 expression, deregulation of ER-associated co-regulators, or deregulation of the cell cycle and apoptosis [ 69].

Any future implementation of the PALM PLUS package should consider continuing the utilization of alternate strategies for motivating HCWs to complete training, such as recognition programs and granting CPD credit, as well as examining HCW motivation in the context of the broader health sector compensation challenges in resource-limited settings such as Malawi.

That mutation promoted utilization of the alternate splice donor site in exon 11, resulting in large amounts of progerin synthesis.

Indeed, we have recently found that illumination of Synechocystis with light that preferentially excites PSII leads to preferential utilization of an alternate nitrogen assimilation pathway over GS-GOGAT pathway [ 47].

Experimental studies have shown a coordinated reciprocal regulation of the folate-dependent and betaine-dependent remethylation of homocysteine to methionine, such that deficiency of either folate or choline and betaine leads to increased utilization of the alternate pathway (37).

Hutchinson Gilford progeria syndrome (HGPS) is caused by point mutations that increase utilization of an alternate splice donor site in exon 11 of LMNA (the gene encoding lamin C and prelamin A).

The combined utilization of direct or alternating electric fields and phytoremediation was designed to decontaminate multi-metal polluted soil at a field scale e-waste recycling impacted site.