In Leuconostoc paramesenteroides the citMCDEFGRP operon, involved in citrate utilization, is located on a plasmid [ 42].
Eighty percent of glucose utilization is located in insulin-insensitive tissues (mainly the brain) and the remaining 20% in insulin-sensitive tissues.
In strains CD and PCL1391, adjacent to a gene encoding a putative membrane-associated transporter upstream of fitA, a nine-ORF gene cluster involved in ribose uptake and utilization is located, which was assumed to be unique to the P. chlororaphis subgroup of the P. fluorescens group [ 17].
Interestingly, numerous genes involved in iron utilization are located in the iron acquisition islands I (CVAR_230-CVAR_0239) and II (CVAR_2806-CVAR_2820) of the C. variabile genome.
It is possible that the cluster is related to heme acquisition rather than siderophore mediated iron uptake, since genes related to hemophore utilization were located adjacent to this cluster.
The hgbA gene was over-expressed, as well as the hugZ heme utilization protein which is located immediately upstream of hgbA [ 13].
Additionally, the neighboring gene Blon_2056 encodes a β-fructofuranosidase, and a prominent homolog, BAD_1330, is located in a fructooligosaccharide-utilization cluster in B. adolescentis (Figure S1).
The study about the problems for the ideal medical care utilization for RA is also a challenge because it is located at the intersection of clinical, sociomedical, epidemiological, and health care research.
A putative allantoinase gene is located adjacent to the genes coding for glyoxylate utilization via the glycerate pathway (ARUE_c36330 36350), however, candidate genes for allantoate conversion to urea and glyoxylate, or to ammonia, carbon dioxide, urea and glyoxylate, were not obvious.
This mismatch between glucose and oxygen utilization becomes particularly large if, to consider the contribution of glycogen, the brain's major glucose reserve is located in astrocytes.
The gene for a presumptive heme receptor, hupA (ASA_3328), that is induced by low iron conditions [ 59], is located near hutZXBCD (ASA_3332 – ASA_ 3336), which encode proteins involved in heme uptake and utilization [ 63].
