The circulation of the blood links the sites of oxygen utilization and uptake.
Very recently, OprG from P. putida, which is 70% identical to P. aeruginosa OprG, was shown to have a high emulsifying activity, leading to the suggestion that it may be involved in the utilization and uptake of hydrocarbons [22].
Notably, several proteins involved in iron utilization and uptake (Fur, cytoplasmic ferritin, Fe-S cluster formation, bactoferrin, siderophore receptor TonB, iron transport protein, iron-dependent alcohol dehydrogenase, and ferric enterobactin receptor) and ribosome structure (L7, L32, S20, S13, S11 S19, L14, L33, S4, L4) were identified as differentially expressed.
Dex was found to inhibit glucose consumption, utilization and uptake leading to a strong inhibition of glycolysis in ALL cell lines and primary ALL blasts cultured ex vivo.
Thus, the three different methods showed that Dex inhibits glucose consumption, utilization and uptake in RS4 11, SupB15 and CCRF-CEM but not in Reh ALL cell lines.
Here, we show for the first time that the GC Dex profoundly affects the leukemic-cell energy metabolism by inhibiting glucose utilization and uptake, and downregulating GLUT1 expression in ALL cell lines.
A quantitative retrospective data analysis will be completed with data ascertained from call centers to determine utilization patterns and uptake of the respective transport systems.
We thus demonstrate that Dex reduced glucose consumption, glucose utilization and glucose uptake by leukemic cells.
Plants have evolved two major strategies to overcome P limitation in the soil, which are P internal utilization and P uptake [ 3].
The utility of FDG is based on the Warburg effect, that is, the ability of MM and virtually all other cancer cells to undergo aerobic glycolysis that results in heightened glucose utilization and FDG uptake rates.
EMD008 was chosen because it lowers ATP/ADP ratios similar to metformin, which should activate AMPK and thereby improve hepatic and skeletal muscle glucose utilization [28] and uptake.
