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Our intention was to perform a longitudinal and systemic investigation to examine the utility of this system to characterize the step-wise events that lead to hepatocarcinogenesis.
We next sought to test the utility of this system for studying key questions in the HBV life cycle.
We describe the utility of this system using Caenorhabditis elegans embryo as a model.
To demonstrate the utility of this system, we show that two interferon-stimulated genes (ISGs), ISG20 and tetherin, restrict HBV spread in NTCP-expressing hepatoma cells.
Thereafter, we explored the utility of this system to present TGF-β1 to encapsulated cells for prolonged time period.
The utility of this system was demonstrated by disruption of nine candidate genes for conidial pigment biosynthesis.
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The utility of this probe system for sensitive detection of amplification products was demonstrated in a real-time PCR format.
We then apply the method to several medical imaging data sets of human vascular structures to exemplify the utility of this coordinate system for analyzing morphology and dynamic geometric changes in blood vessels throughout the body.
We further demonstrate the utility of this organoid system for modeling the teratogenic effects of Zika virus on the developing brain and identifying more susceptibility receptors and therapeutic compounds that can mitigate its destructive actions.
To illustrate the utility of this catalytic system, we designed a colorimetric assay, in which a synthetic oligonucleotide with a sequence complementary to the G-quadruplex DNA was used as the target.
Next, we demonstrate the utility of this recombination system by using it to target cre to the 3′ end of the mouse neuron-specific enolase (Eno2) gene carried on a 250-kb BAC, which made it possible to generate BAC transgenic mice that specifically express Cre in all mature neurons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com