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However, conclusive data regarding the clinical validity and utility of this screening tool, both for the originally included common autosomal and sex-chromosomal aneuploidies as well as the more recently added chromosomal microdeletion syndromes, have lagged behind.
The ROC curve analysis further confirmed the utility of this screening technique for early detection of malignant changes in the oral cavity.
Thus, we believe that the strategy of using redundant libraries and focusing only on hits isolated multiple times will greatly increase the utility of this screening technology for the discovery of diagnostically useful antibodies.
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Therefore, we gauged the utility of this screen as a further method of intervention under the assumption that hospitals have the facilities to segregate colonized (both asymptomatic and symptomatic) and non-colonized patients.
To date, few data have been published regarding the utility of the screening urinalysis in this role.
Each knockdown resulted in distinct vascular phenotypes demonstrating the utility of the screening method used and the importance of the genes identified.
Diagnostic utility of the screening tools and QST was determined using the neurologist's clinical assessment of moderate/severe neuropathy as the gold standard.
To demonstrate the utility of the screening platform, we undertook a proof-of-principle pilot screen with the MicroSource Discovery Systems Spectrum Collection.
The AUC for the discriminant score analysis reached nearly 100% and conclusively proved the utility of the screening technique for early detection of oral cancer.
Receiver-operator curve (ROC) analysis was conducted to examine the diagnostic utility of the screening instrument compared to the CIDI [ 40].
This screen isolated new unc-51 alleles (demonstrating the utility of the screen) and rpm-1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com