Sentence examples for utility of this class from inspiring English sources

Generating novel microtubule targeting agents with novel pharmacology could dramatically expand the utility of this class of drugs.

Moreover, the lack of controlled data demonstrating the ability of ketamine to sustain the antidepressant response with repeated administration leaves the potential clinical utility of this class of drugs in question.

The emphasis of the effort had been on novel catalytic asymmetric processes and their application to complex target synthesis designed to demonstrate general synthetic utility of this class of organosilanes as new versatile platforms for asymmetric synthesis.

Despite robust preclinical data demonstrating anti-tumor activity of first-generation Hsp90 inhibitors in prostate cancer, poor clinical responses initially cast doubt over the clinical utility of this class of agent.

Here we review the details of the mechanism of the reactions promoted by the serine recombinases and discuss how these not only limit the utility of this class of recombinase but also creates opportunities for the engineering of new enzymes.

Abciximab is the most extensively studied agent to date, but trials of other antagonists, particularly eptifibatide and tirofiban, support the utility of this class of therapeutic agents as a whole.

The utility of this new class of nonpeptidic foldamers for biological applications is highlighted by high resistance to proteolytic degradation.

In the 1970s, Abramovitch and Yamada described the synthesis and electrophilic reactivity of sulfonyliminoiodinanes (RS O2 N═IPh), demonstrating the utility of this new class of reagents to function as nitrene equivalents.

In the present study, we investigated a variety of metabolic consequences following subchronic Boc5 treatment of DIO mice to explore the potential therapeutic utility of this new class of GLP-1 mimetics.

As such the utility of this drug class in community or hospital acquired infections meningeal infections with these organisms remains unchanged.

Imidazole-containing compounds have received considerable attention in the search for leishmaniasis chemotherapy due to the success of agents such as ketoconazole, miconazole, econazole, and clotrimazole in treating fungal infections, thus lending credence to the possible utility of this broad class of compounds in other types of infection.