Sentence examples for utility of these molecules from inspiring English sources

The results point to the utility of these molecules and of the comet assay as possible predictive markers.

However, clinical utility of these molecules as prognostic markers is limited by the use of ELISA tests for their detection in fresh or frozen tissue [ 46].

It also demonstrates the utility of these molecules as chemical tools for dissecting the basic biology of MCL-1 and the promise of small-molecule MCL-1 inhibitors as potential therapeutics for the treatment of cancer.

Unfortunately, the clinical utility of these molecules as biomarkers is limited to use as a laboratory test for basic cancer tissue detection and they are not yet used as prognostic tool [ 20, 49].

These preliminary enzymatic studies have provided useful information for a better understanding of the involvement of conjugative metabolism in the biotransformation of synthetic stilbenoids in humans and for assessing the potential utility of these molecules as novel chemotherapeutic agents.

Based on the review of literature (as summarized in Table 1), MMPs and TIMPs cannot be applied for the routine diagnostic of TA yet and the clinical utility of these molecules remains to be established.

Careful selection and combinations of biomarkers with relative specificity to disease states (for example, the observed association between Ang-2 and ARDS/pulmonary leak, or the differential association of sVCAM and sE-Selectin in fungal sepsis) would be one way of improving the clinical utility of these novel molecules.

The bifunctional nature of HGF on both Purkinje cells and Bergmann glia highlight the potential therapeutic utility of this molecule for the treatment of SCA7 and related disorders.

The utility of this molecule in treating platinum-resistant disease will hopefully be determined by a randomized, double-blinded, placebo-control study examining paclitaxel with and without concurrent MORAb-003 (NCT00738699).

Further studies will concentrate on characterising the expression of the PASD1 protein as this will have more significance as to the clinical utility of this molecule; monoclonal antibodies are currently being raised to both the short and long forms of the protein.

The clinical utility or application of these molecules as biomarkers in sepsis; however, is limited by a lack of standardization in analytical assays, a lack of data regarding receiver operating characteristics and a lack of validation.