Sentence examples for utility of the mouse from inspiring English sources
Such differences further undermine the utility of the mouse as a model.
TCE offers an attractive case study for examining the utility of the mouse population for characterizing variability.
To gain molecular insight into the mechanisms through which p15Ink4b protein affects erythropoiesis, we explored the potential utility of the mouse multipotent blood progenitor cell line, EML.
In addition to highlighting target genes that warrant further analysis, the work validates the utility of the mouse model for the investigation of childhood asthma pathogenesis.
The utility of the mouse as a model for screening of lead gamma-secretase inhibitor candidates against Notch endpoints has been previously described [ 41].
The study also highlights the utility of the mouse as a model for myopia, particularly in conjunction with new technologies that can measure ocular dimensions and optical properties with high precision.
Thus, we have shown that CD-1 mice represent an excellent genetic mapping resource of broad utility to the mouse genetics community.
In summary, our phenotypic analysis of the hTNFα TG line demonstrates the utility of this mouse line as a model for multiple human diseases in which chronically elevated TNFα levels are present including its established use in studies of RA.
This study therefore highlights the utility of these mouse models, which provide a rich resource for the longitudinal analysis of molecular changes and biomarkers associated with HCC that could be exploited further for therapeutic targeting.
To confirm the utility of the R26PR mouse model, we mated R26PR mice to the hematopoietic-specific Cre-recombinase-expressing line Tg(Mx1-cre)1Cgn/J (hereafter called Mx1-cre) to determine whether deletion of the FS cassette and subsequent expression of Prdm14 in R26PR animals would also result in leukemia.
These results support the utility of these mouse HSV-2 susceptibility models for predicting microbicide-induced toxicities that increase HIV susceptibility in women.
