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It's not a perfect solution, and it takes some extra planning because it's not the way things have always been done, but it's possible, and inexpensive, and doesn't affect the utility of the database.
Instead, the new focus will be on improving the utility of the database and incorporating other taxonomic catalogs.
Transcription data derived from Illumina RNA-seq analysis of various tissues under normal and stress conditions (Mizuno et al. 2010; Oono et al. 2011; Kawahara et al. 2012, 2016) have been added to enhance the utility of the database in understanding transcriptional regulatory networks.
Also, the utility of the database shall be exemplified by a few examples.
To illustrate the utility of the database, we also provide an in-depth study of five repetitive genes.
MG and NdeW represent study groups of the PCR-MN and contributed to the utility of the database.
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In addition to a short introduction to microbial rhodopsins, the homepage provides a brief description of the database content and clickable icons with direct links to the major utilities of the database, including database and sequence similarity searching, and phylogeny.
The major utilities of the database, including database browsing/searching and live data statistics, as well as a detailed help document, are highlighted on the homepage by clickable icons with direct links to the respective main page.
The utility of this database is reflected in the fact that several of these cell lines have already been shared and used to discover a novel potent candidate drug for treatment of GBM (Kitambi et al., 2014), as well as in a number of other studies (Wee et al., 2014, Babateen et al., 2015, Schmidt et al., 2013, Savary et al., 2013, Yu et al., 2013).
The utility of this database is demonstrated in two examples: the AUC change comparison between hepatic impairment studies and the pharmacologic inhibition of CYP3A4, and the AUC change comparison between renal impairment and pharmacologic inhibition studies.
To independently demonstrate the utility of this database in defining enrichment of transcripts in glomeruli, RT-PCR comparing the level of expression of 19 transcripts enriched in the glomerular SAGE library with that in lung, spleen and liver was performed.
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