Sentence examples for utility of expression from inspiring English sources

As independent proof of the utility of expression data, this resource has been used previously to support single-gene, organ-specific and genome-wide studies.

Hybridization artefacts caused by SNP's [ 10], non linearity among probes, inability to detect splice variants and, importantly, the bias towards available information (i.e. only transcripts with corresponding probes on microarray can be examined), limit the utility of expression microarrays.

Karyotyping by expression microarrays, as described by Ben-David et al. (2013), extends the utility of expression microarray data by providing some limited information on the status of chromosomal aberrations in a sample.

To further evaluate the utility of BAALC expression to monitor therapy response, BAALC expression was analyzed in 358 diagnostic and follow-up samples of 57 patients showing high BAALC expression at diagnosis.

We present our proof of principle studies using a homotrimeric ion channel (ASIC3) and a heterodimeric transporter (SLC7A5/SLC3A2) as examples, and demonstrate the utility of transient expression coupled with FSEC in optimizing membrane protein expression.

The main objective of this study is to evaluate the diagnostic utility of the expression of a panel of miRNAs in breast cancer and compare their expression with the expression of the proteins they regulate.

It is well-established in previous literature that the utility of gene expression models extends beyond the ability to predict the expression levels of individual genes.

Interestingly, JARID1B expression is dynamically and temporarily regulated, thereby negating the utility of gene expression profiling.

While this approach demonstrated the utility of leveraging expression data to identify candidate CNV regions and genes whose expressions might be affected by the candidate CNV, the identified regions were often large and harbored many genes.

Therefore, these correlations may underestimate the prognostic utility of CD14 expression, however, further studies will be required to clarify how strongly CD14 expression in the skin correlates with progressive skin disease.

We and others have shown the potential clinical utility of gene expression profiles in cancer research, in which the identification of patterns of gene expression within tumors has led to the characterization of tumor subtypes, prognostic categories and prediction of therapeutic response [33] [37].