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Following further validation, the signature may have clinical utility in combination with other host response signatures for diagnosing and managing patients with systemic inflammation.
"In our opinion, the key to Encysive's success will rest in the company's ability to capture patients who do not respond to or become tolerant to Revatio, and to establish utility in combination with Revatio," said UBS. "Further, should our worldwide PAH market estimate of 100,000 patients prove conservative, significant upside to our Thelin estimates could exist".
Although the contribution of some elements to the inter-vector distances is much greater than others (which is also influenced by general structural features of the dataset), all the described elements were kept for their potential utility in combination with weighting factors (e.g. in a machine learning context).
Nevertheless, phylogenetic analysis would have enabled identification of viable substitutions for several Phe positions targeted in the different GFP constructs made, indicating its utility in combination with random approaches.
The data presented in Table 1, as well our previously published report [ 8], suggested that hCG-sLHCGR and sLHCGR had utility in combination with PAPP-A, free βhCG and other markers, but might be limited in use as independent markers.
It may have limited utility in combination with additional screening tests or for selection of at-risk populations, but cannot be recommended for routine use as a screening tool in clinical practice.
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As a benefit from the system's design, most tasks in Plan 9 can be accomplished by using ls, cat, grep, cp and rm utilities in combination with the rc shell (the default Plan 9 shell).
In addition, we performed two two-way sensitivity analyses to test the most uncertain parameters, such as a variation in utilities in combination with the various DBC tariffs, and the variation of utilities in combination with the probability of aspiration.
Aleuria aurantia lectin for example has affinity for α 1-2, -3, -4 and α 1-6 fucosylated glycans [ 12, 47], and might be of some utility, perhaps in combination with ConA.
This study investigated the potential utility of oxovanadium in combination with thiourea non-nucleoside inhibitors (NNIs) of HIV-1 reverse transcriptase (RT) for the development of an effective dual-function anti-HIV spermicide.
Recent studies showed the potential utility of TDF, in combination with PbtO2, to optimize the management of CPP in brain-injured patients.
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