Sentence examples for utility as a marker from inspiring English sources

It is important to investigate its specificity in order to establish its clinical utility as a marker of coronary heart disease.

Oct4 plays a critical role in maintaining pluripotency and self-renewal of ES cells (Niwa et al., 2000; Pesce and Scholer, 2001), but its utility as a marker of pluripotency has been challenged recently by studies suggesting that it is expressed in a variety of differentiated cells, including peripheral blood mononuclear cells (PBMCs) (Tai et al., 2005; Zangrossi et al., 2007).

Overall, the value of stroke volume variation derived from FloTrac™ changed in tandem with the intraoperative volume status, indicating its utility as a marker of circulatory hemodynamics.

Regardless, among those exposed to brain tissue in this way reduced IFNγ secretion may have utility as a marker for disease severity.

SLO is a highly immunogenic streptococcal toxin that induces ASLO antibodies in a majority of subjects following streptococcal pharyngitis, hence its clinical utility as a marker.

However, the small size and short biologic half-life of annexin V limit its utility as a marker of therapy response.

CD146 is considered a panendothelial-specific marker, but its utility as a CEC marker in cancer patients remains unclear.We analyzed the expression of CD146 on mononuclear blood cells, primary tissue endothelial cells, and malignant and normal tissues by flow cytometric and immunohistochemical analyses.

Tumour leptin expression determined by immunohistochemistry has potential utility as a predictive marker of resistance to cytotoxic chemotherapy, and a prognostic marker independent of therapy in gastro-oesophageal adenocarcinoma.

The relationship between disease severity, outcome, and 14-3-3η 14-3-3η 14-3-3ηexpression along wash thevaluated of14-3-3η alongmarker in informing therapy response.

Furthermore, we demonstrate that microglia specifically repress Itga4 (CD49D), enabling its utility as a discriminatory marker between microglia and BMDMs in primary and metastatic disease in mouse and human.

This review summarizes recent studies exploring the role of LDH-5 in cancer growth, its utility as a tumor marker, and developments made in identifying and designing anti-LDH-5 therapeutic agents.