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In this paper we attempt to clarify some of these issues and to provide guidance on the design of clinical trials for evaluating the clinical utility and robustness of pharmacogenomic classifiers.
This case study demonstrated the utility and robustness of the new method, indicating that the most important events were south-to-north dispersal patterns, as one would expect, with secondary faunal interchange among regions.
These findings suggest how data gathering activities might be better sequenced and how metrics might better constructed to improve the utility and robustness of both participatory and non-participatory landscape change assessments.
The utility and robustness of the method for the application of various basis functions are evaluated with the following four sets of orthogonal polynomial series, i.e., the Chebyshev orthogonal polynomials of first and second kind, Legendre orthogonal polynomials of first kind and Hermite orthogonal polynomials.
To illustrate the utility and robustness of this signature, we determined its discriminative power on another 19 completely independent datasets.
The breadth of applicability (Figure 3a, Figure 3b) and efficiency demonstrated (Figure 3a, Figure 3b, and Figure S2) illustrate the general utility and robustness of the approach.
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The utility (and robustness to uncertainty regarding the base slope) of the results in applications is demonstrated in the regional example of the Akrotiri Coastal Aquifer, Cyprus.
More research targeted on identifying and evaluating the utility, transparency, and robustness of different methods including the questions they are suitable for answering will be useful in the future as the application of improved methods becomes more widespread (Krauth et al. 2013).
We demonstrated the utility, flexibility, and robustness of the ALERT algorithm, which can serve as a valuable tool for communities, schools, hospitals, and other institutions looking for a method to objectively define a period when, for example, enhanced patient contact precautions, empiric therapy, or other prevention measures should be implemented.
In response to the combined effects of growing energy demand and the impact of de-regulation of the electrical energy industry, pro-active utilities are ensuring flexibility and robustness of their networks, by upgrading or installed capacity in both transmission and distribution.
These results confirm the utility and the robustness of SNP analysis when dealing with V. vinifera cultivars, particularly in consideration of the cost and labour required for a resequencing strategy.
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