Sentence examples for utilised this approach from inspiring English sources

Here we utilised this approach in conjunction with fragment-based drug-discovery.

In this study, we have utilised this approach to determine whether depletion or augmentation of intracellular GSH status impacts upon the pharmacokinetics or hypoxia selectivity of 64Cu-ATSM.

The previous production of a selective KLK4 inhibitor utilised this approach by grafting a preferred substrate sequence into the β-sheet of SFTI-1 [16].

Schwarz et al. [17] utilised this approach extensively to screen siRNAs for the targeted silencing of mutant Htt and SOD1 genes and reported that nucleotide mismatches in the 3' region of the siRNA guide strand could allow greater single nucleotide selectivity than those placed centrally, in particular mismatches at position 16.

We utilised this approach as a descriptive tool.

A number of recent high-impact clinical studies, such as the ROSSINI trial and National Appendicectomy Audit, have successfully utilised this approach [ 15, 16].

Great success has been demonstrated utilising this approach, particularly in the field of vaccine delivery.

Therefore, understanding the mechanisms by which tumours adapt to VEGF blockade is important in optimising therapeutic regimens utilising this approach.

Ziv and colleagues have reviewed the use of simulation from the patient safety perspective and suggest that there is an ethical imperative for medical educators to utilise this approach [ 22], while Cook and Triola have explored the potential for computer-based 'virtual patients' to enhance clinical reasoning [ 23].

The paper concludes with a discussion section that surfaces the key issues and challenges inherent in utilising this MBSE approach across the contractual boundary and ways that the selected approach could address these.

This is believed to be the first study to utilise this methodical approach to define rurality or relational place.