Sentence examples for utilised in vitro from inspiring English sources
Therefore, we utilised in vitro assays to determine whether iFGFR1 directly induces expression of IL-1β in mammary epithelial cells.
However, to our knowledge, no previous study has utilised in vitro and in vivo models to evaluate the therapeutic efficacy of everolimus.
Since this publication, the presence and role of hypoxia in the endometrium has remained the subject of intense debate, with conflicting results from different laboratories utilising in vitro, ex vivo and in vivo models9,10,11,12,13.
Preclinical testing should comprise a series of investigations, initially utilising in vitro and in vivo mechanistic assays.
The compounds were analysed experimentally, utilising in vitro hybridization and DNA polymerase incorporation assays as well as an in vivo HNA-dependent DNA synthesis assay.
In their work, they utilise in vitro cultured myogenic cells and also a canine model of DMD that shows strong phenotypic similarities to human DMD patients, demonstrating that the use of multiple complementary approaches and model systems can allow complex disease mechanisms to be elucidated.
Many experimental models have utilised either in vitro studies of isolated cell lines or animal and human studies where LPS is exposed to the circulation by parenteral injection.
To define the manner by which IFN-γ might regulate catabolic responses induced by IL-1β in humans we utilised an in vitro model system using the structural cells that constitute the inflammatory pannus, namely, FLS cultured from RA synovial tissue specimens.
This tool has been utilised in the field of in vitro toxicity testing of airborne nanoparticles/chemicals [19, 23] and for the first time with diluted whole smoke in vitro[22].
Although the in vitro approach utilised in this investigation represents an extreme reductionism relative to the complex situation in the intact organism, it can provide an insight into specific effects of model agents.
On the other side, the homemade cDNA microarrays have been utilised in most of the in vitro studies reported in bladder cancer.
