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kConFab provided the research resource utilised in this report.

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The five stages of their framework; identifying the research question, identifying relevant studies, study selection, charting the data, and collating, summarising and reporting results were utilised in this study.

A parent-report version (PEDE) is also utilised in this study [ 24, 25].

It was these three datasets that were utilised in this study.

The 3D classification method utilised in this study is discussed in the next section.

The strain utilised in this study (B5055) is of the K2 O1 serotype.

A national representative sample was utilised in this study.

Purposive random sampling was utilised in this study.

For this reason, Matrigel™ matrices were not utilised in this study.

The in vivo biodistribution of [Zr(ox 4]4– was consistent with previous studies utilising murine models, and so only a single animal was utilised in this study.

The constructs utilised in this study are summarised in Figure  1B.

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