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Transdermal oxybutynin could be seen, for example, as a reasonable, but understudied and not widely utilised alternative.
A widely utilised alternative to HDPR has been the use of hypofractionated radiation schedules, which are considerably less resource and time intensive.
4 12 19 In a large descriptive study (n=159) using repeated measures before and after haematopoietic stem-cell transplantation (t=30, 60, 90 and 180 days), Sirilla and Overcash 18 reported that faith, prayer and spiritual healing were the most utilised alternative support resources identified by patients, a finding that is consistent across cancer groups.
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The fixation of positively charged residues at position 110 112 in the βF βG loop of VP1 of SAT1 isolates is thought to correlate with the acquisition of the ability to utilise alternative glycosaminoglycan (GAG) molecules for cell entry.
Because the wild fisheries, from which FO is obtained, are currently fished to the maximal sustainable levels there is pressure to utilise alternative lipid sources in aquaculture diets.
To address this, epidemiological researchers have sought to utilise alternative data sources including medical and pharmacy claims databases similar to the administrative databases held by Italian LHUs [ 30– 30].
Oestrogen receptor-positive breast cancers develop resistance to anti-oestrogens by utilising alternative growth factor pathways as observed in our tamoxifen-resistant cell line (TAMR).
Suggestions include removing hot water sources, automating the mixing process so that workers do not control the water temperature, or utilise alternative detergents that are not enzymatic based.
We suggest that the metabolic mechanism by which moderate DR inhibits CT-2A brain tumour growth involves a failure to utilise alternative energy substrates.
Use of alternative yeast species (for example, S. kudriavzevii [ 51]) and existing recombinant industrial strains (for example, see [ 52]) that can utilise alternative substrates and agro-industrial feedstocks for the production of squalene and ethanol is also of interest.
Moreover, loss of one copy of the MAT-bearing chromosome 5 of C. albicans is required for adaptation to utilise alternative carbon sources, and to drive the white/opaque transition [ 30].
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