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Happé and Frith, however, utilised a small sample size (18 CD children and 8 controls) and a first-order task which, if used with individuals whose mental age is more than six years, is subject to ceiling effects [ 21].
However, it is important to note that this discovery phase utilised a small sample cohort and the candidate gene expression changes require further validation in a lrger independent cohort.
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Another striking finding was that two of the four studies that did not confirm the current study's hypotheses utilise a small sample.
The 2008 survey was part of a continuous survey running until 2011, utilising a smaller sample size than previously.
Most importantly, the study utilised a relatively small sample, which might have increased likelihood of type-2 errors, and the findings should therefore be considered with caution until there is evidence of replication.
Twenty is a small sample.
Yes, it is a small sample.
That, too, is a small sample.
First up: generalisation from a small sample.
Flynn's small sample size may be overwhelmingly impressive, but it remains a small sample.
Such a small sample introduces a high margin of error.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com