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The times required for procedures, the grade of staff that usually administers the procedure, and the usual pathway were overall averages, gained from speaking to clinical staff either at the selected hospital, or where not available, from other UK hospitals.
The liver breaks down paracetamol, but if the usual pathway is overloaded, another pathway takes over that produces a toxic substance.
The structural modification of gatifloxacin and the rationale for the modification is summarized in Schemes 1 & 2. 1,4-dihydroquinoline-3-carboxamide (4 12) and 1-4-dihydroquinoline-3-carbohydrazine (13 14) analogues of gatifloxacin, formation proceeds via the usual pathway of nucleophilic substitution (Scheme 1).
The caveat "as appropriate" is, to me, the proverbial "fly in the soup" that allows actors responsible in theory at least for effective DRR to see the SFDRR as a permit to continue along the "business as usual" pathway until the next climate, water, weather, or geohazard reminds them that maybe developing a "culture of prevention" was a more appropriate pathway to have chosen.
Reductive carboxylation of 2-methylbutyrate is probably the route for isoleucine biosynthesis [24], as M1 lacks a gene encoding a homoserine kinase needed for the usual pathway from threonine (Table S1).
This is the usual pathway for patients with breast complaints in Germany.
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They've chosen this approach to disrupt the usual pathways for non-profit engagement, which is usually a closed, one-way path.
In the girl who is looking at the strobe or a stuffed animal in her crib, the visual input continues on its usual pathways, one of which ends up in the visual cortex.
Melanoma cluster 2 cells completely revolutionized the usual pathways of ganglioside biosynthesis present in melanocytes and acquired the expression of GM1 and GM2 synthases.
We predict that the Y64H amelogenin mutation results in a failure to traffic and secrete protein along the usual pathways resulting in the observed accumulation of amelogenin and ameloblastin in the ameloblast endoplasmic reticulum.
At treatment stopping, neoangiogenesis becomes intensively stimulated through the usual pathways previously blocked by the drug and through alternative pathways induced by the drug treatment, through the activation of pre-existing invasion program or cancer cell phenotypic change and selection of clones resistant to hypoxia [ 4- 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com