Sentence examples for using various experimental approaches from inspiring English sources

Using various experimental approaches, we show that concerted, low-affinity interactions of the PSIP1-PWWP domain with both nucleosomal DNA and methylated histone tail result in specific and high-affinity binding to H3K36-methylated nucleosomes.

The role of MYC in BL development, as well as the tumor suppressor pathways employed in an attempt to control lymphocyte proliferation, have been studied in depth using various experimental approaches.

The aim of this work was to delineate the functional characteristics of GL15 cells using various experimental approaches, including the study of morphology, mechanism of induction of intracellular Ca2+ increase by different physiological agonists, and the presence and permeability of the gap-junction system during cell differentiation.

A number of approaches have been employed to assess the contribution of particular starter strains to the relevant pathways, ranging from simple culture techniques to biochemical profiling of key enzymes, and quantitative analysis of sample products using various experimental approaches and/or sensory panels.

Our study used various experimental approaches to examine the mutational mechanisms operating within mature microsatellites, which we define as alleles that are not expected to mutate to lengths below or at the threshold for microsatellite mutational behavior in one round of replication.

As a result, state prisons have had to resort to using various experimental drugs, with different levels of success.

We will be able to refute this hypothesis by using various experimental protocols.

However, using various experimental techniques, including mutation of the putative Bax-binding residues, co-immunoprecipitation in various conditions, surface plasmon resonance, split luciferase complementation assay and different pull-down approaches, we did not find any evidence for such interaction (data not shown).

As these sequences are available from commercial sources, they can be readily obtained and tested using the various experimental approaches available to Xenopus such as gain of function studies by microinjection.

To date, various experimental approaches used to clarify the molecular mechanisms of frequency-decoding of GnRH by the gonadotrope have provided only partial explanations (e.g. [5], [13], [24] [26]).

Because of the various experimental approaches used, it is currently not clear which adenosine receptors are expressed in the urothelium or what is their exact subcellular localization in the urothelial cells [ 96, 101].