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QALYs were derived from responses to the EQ-5D-3 L at baseline, 6 weeks and 6 months using valuations from the UK general population.
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Utilities can be elicited directly from patients using valuation techniques (such as the standard gamble or time trade-off), or through the use of generic preference-based measures such as the Health Utilities Index (HUI) [ 7] or EuroQol EQ-5D survey (EQ-5DTM is a trademark of the EuroQol Group) [ 8- 10].
Other approaches to predicting or estimating utilities from the QLQ-C30 include using valuation studies (such TTO) [ 12].
We use valuation tools in order to study the buyer.
To our knowledge, no study has assessed the health state valuation of deafness for adults in India, and following WHO guidelines on CEA, we use health state valuations from the Global Burden of Disease study [ 9].
The EQ-5D utility index was calculated using the valuation set from the Korean population [ 10].
The study presented sufficient details, which enabled the adjustment of resource valuation using data derived from the German study.
Different valuation techniques are used to obtain health state valuations from the general public.
The preference weights and the calculation algorithm we used in this study were determined in the UK using data from the Measurement and Valuation of Health Survey [ 30].
These preference weights and an algorithm for calculating the EQ-5D index were determined in a UK population using data from the Measurement and Valuation of Health survey [ 7].
For each of these health states, an independent samples t-test was used to determine whether the mean valuations from the two studies are statistically significantly different.
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