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EPA's risk assessment, released on 14 April, relies on troubling data from a study using two generations of rats.
In an attempt to determine how such assays would perform in a clinical laboratory, we evaluated the analytical variability of Affymetrix microarray probesets using two generations of human Affymetrix chips (U95Av2 and U133A).
Genotyping was done using two generations of the Mouse Universal Genotyping Array: MUGA [ 16] (7,800 markers) and MegaMUGA [ 17] (78 k markers).
There was no clear trend in type I error when using the measured genotype approach (1) or ignoring family structure: in some scenarios using five generation of pedigree gave a more conservative type I error, whereas in other scenarios it was more liberal than using two generations of pedigree information (Table S1).
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The strategy of using three generations of a family increased the robustness of detecting rare mutations, showing a similar performance between common mutations and rare mutations (Additional file 1, Figure S4).
We used two generations of a commercial line of chickens selected for high egg-laying.
To characterize the panicle blast resistance of Miyazakimochi in more depth, we performed field assays using three generations developed from a cross of Miyazakimochi and Bikei 22.
In this study, we use two generations (G8 and G10 cohorts) of an advanced intercross line between DA and PVGav1 to reproduce linkage to Vra1 and to fine-map this region.
To illustrate the advantages of using RIL in a joint scaling context, we used
We exposed zebrafish embryos to ANS crude oil weathered using two methods: generation of a WAF by an overnight high-energy spin of an oil water mixture and incubation in the effluent from a column loaded with oiled gravel (OGE) or control (clean) gravel (CGE).
Bayesian analysis was performed with MrBayes [39], using two runs of 1 million generations sampled every 100 generations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com