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Since psychometric documentation of the SAT was lacking, a post hoc analysis was conducted using trials data to validate the SAT [ 24].
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Although both of these procedures may seem sensible, a large amount of research has showing that using trial data to choose the method of analysis can lead to biased results and incorrect type I error rates [ 21- 24].
The investigative team will approve the requests paper and abstracts produced using trial data according to predetermined publication priorities based on appropriateness and scientific merit.
GPPAQ scores from participants' computerised primary care records (n = 56) were compared to PACE-Lift trial recorded GPPAQ scores, using trial data closest in time to the primary care record.
[1] The standard fashion of applying the results of a large clinical trial to an individual patient requires building a statistical model using trial data and applying the model to the patient according to known measured risk factors of that patient.
A within trial evaluation will compare the outcomes and cost up to one year post-injury using trial data and index hospital episode data.
Using trial data for a study like this has advantages and disadvantages.
Health resource data was obtained as part of a cost-utility analysis using trial data from the CanChange study.
Another possible limitation of using trial data is that the inclusion and exclusion criteria used in these trials provide a restriction not present in clinical practice.
Two other studies on the associations between weight or BMI and changes in breast measures used trial data [ 7, 38].
The third area of uncertainty tested the effect of using imputed data rather than complete cases; the third sensitivity analysis used trial data with missing values imputed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com