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[1] The standard fashion of applying the results of a large clinical trial to an individual patient requires building a statistical model using trial data and applying the model to the patient according to known measured risk factors of that patient.
A within trial evaluation will compare the outcomes and cost up to one year post-injury using trial data and index hospital episode data.
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Another possible limitation of using trial data is that the inclusion and exclusion criteria used in these trials provide a restriction not present in clinical practice.
The investigative team will approve the requests paper and abstracts produced using trial data according to predetermined publication priorities based on appropriateness and scientific merit.
Using trial data for a study like this has advantages and disadvantages.
Health resource data was obtained as part of a cost-utility analysis using trial data from the CanChange study.
Since psychometric documentation of the SAT was lacking, a post hoc analysis was conducted using trials data to validate the SAT [ 24].
14 The IRIS model was based on fewer assumptions about women's trajectories into and out of abuse and we used trial data instead of pilot data.
Two other studies on the associations between weight or BMI and changes in breast measures used trial data [ 7, 38].
Firstly, they are simply wrong about the Cochrane Library (which simply produces good reviews of published literature): it does not only use trial data.
The third area of uncertainty tested the effect of using imputed data rather than complete cases; the third sensitivity analysis used trial data with missing values imputed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com