Sentence examples for using traditional approaches of from inspiring English sources

Using traditional approaches of human genetics, such as positional cloning, meiotic mapping, physical mapping and candidate-gene sequencing [ 15], PKD1 in PKD [ 16] and NPHP1 in NPHP [ 17] were identified as initial causative genes of ciliopathies in the late 1990s.

Determining the distribution of Cx proteins in the CNS using traditional approaches of in situ hybridisation and immunohistochemistry has provided variable results and connexin-specific protocols required for both methods are not readily amenable to dual labelling (Sohl et al. 2005).

Despite the historic success of the commercialization of new technologies using traditional approaches, the increasing complexity of materials coupled with their longer development cycle time compared with those for products has resulted in many missed opportunities for new materials and processes insertion.

10 Efforts to understand the functions of sialic acids using traditional approaches have been stymied by genetic redundancy of sialyltransferase family members and a lack of tools for probing sialic acids at the biochemical level.

However, the majority of processing technologies are difficult to study using traditional approaches, due to the opacity/impermeability of the construction materials, as well as employed fluids, and geometric complexities of such systems.

Bacterial protein export requires a wide range of protein interactions between soluble and transmembrane proteins, many of which have been difficult to detect using traditional approaches especially in the context of living cells.

Preparation of IDF curves using traditional approaches is a difficult task due to lack of short duration (<24 h) rainfall data other than daily rainfall data in Bangladesh.

The computationally designed polymer demonstrated superior selectivity in comparison to the polymer prepared using traditional approach, a detection limit of 25 μM and good stability.

However, over the past 15 years, several investigators have identified on a gene-by-gene basis using traditional experimental approaches regions of gene promoters, and in some cases specific sequence elements, that are important for proper gene expression [ 4- 12].

The majority of scales in the health and social sciences have been developed using traditional psychometric approaches involving the assessment of validity and reliability [ 12].

The control of nonlinear non-minimum phase processes by using traditional geometric approaches has lead to the development of specific design methods, such as the statically equivalent output approach.