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Using this probe, we found that human breast cancer cells undergo constitutive endocytosis more rapidly than do matched noncancerous cells.
Using this probe, we tested the skin response to local cooling, down to 15 °C, and its reproducibility.
Using this probe, we find that caspase-6 undergoes a conformational change and can bind substrates even in the absence of cleavage of the proenzyme.
Using this probe, we successfully quantified >4000 proteins modified by 4-hydroxy-2-nonenal (HNE) of high confidence in mammalian cell lysate and combined with a tandem-orthogonal proteolysis activity-based protein profiling (TOP-ABPP) strategy, we identified ~400 residue sites targeted by HNE including reactive cysteines in peroxiredoxins, an important family of enzymes with anti-oxidant roles.
Using this probe, we identified several subunit selective small molecule inhibitors of the parasite enzyme complex.
Using this probe, we photoactivated a small region of the cell cortex of a mitotic cell and allowed the cortex to become saturated with fluorescence.
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Using this probe one retarded band is observed.
with extensive clinical experience in FISH interpretation using this probe.
Here we use this probe and others to examine polyp-stolon junctions in Podocoryna carnea Sars, and Hydractinia symbiolongicarpus Buss & Yund.
Simultaneously, glucose oxidase catalyzes the oxidation of glucose to produce gluconic acid and H2O2, so we can use this probe to detect glucose.
We have used this probe to determine the size of transport complexes of lipidated Shh in culture medium and expression levels of endogenous lipidated Shh in pancreatic ductal adenocarcinoma cell lines through quantitative chemical proteomics, as well as direct visualisation of the probe by fluorescence microscopy and detection of cholesterylated Hedgehog protein in developing zebrafish embryos.
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