Sentence examples for using this mutation from inspiring English sources

Therefore, we decided against using this mutation in our S. Typhi vaccine vectors.

We are currently using this mutation to understand the mechanism of decreasing intracellular H2O2 concentrations.

Using this mutation rate, IM calculates mutation rate scalars for the other loci and uses a geometric mean of all mutation rates to convert divergence times to demographic scales.

Using this mutation rate estimate of 8.4E-9, we date the splits between S. mimosarum and S. tentoriicola at ~8 million years ago and between S. lineatus and S. mimosarum/S.

The Asteraceae-specific rate was used for conversions, but because the average plant mutation rate (5 × 10−9) estimated by Wolfe et al. (1987) has been used in a previous demographic analysis of Senecio (Muir et al. 2013), parameter estimates were also scaled using this mutation rate for enhanced comparability between the studies.

The study was designed to test the hypothesis that an improvement in PFS can be achieved using this mutation-targeted treatment strategy when compared to previous studies.

However, deletion of the BK channel causes disruption of circadian behavioral rhythms in Kcnma1−/− mice and slowpoke flies [14], [19], providing the opportunity to use this mutation in mouse to study the relationship between how a single ionic current regulates SCN-level rhythms and how this current regulates behavioral timing.

We used this mutation rate to calculate the probable domestication time of yaks.

The frequency of this mutation in individuals who have become deaf following aminoglycosides is 13% 60%, 12 13 a frequency far greater than that in the hearing population; and in countries such as Spain and China, where aminoglycosides are widely used, this mutation accounts for 27% of cases of familial progressive deafness.

Since previous NMR studies demonstrated that this mutation abolishes binding to methyl-CpGs without affecting the structure of the MBD or the rest of the protein (Free et al., 2001), we used this mutation to assess the necessity of methyl-CpG binding in both RTT and MECP2 duplication syndrome.

We note that there are a number of sources of error that can affect the accuracy of a molecular clock [ 84] and that using an alternative rate would alter our time estimates, but we use this mutation rate to give a rough idea of the divergence times in A. lugubris.