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Further experiments using this experimental model should be performed to investigate the mechanisms and consequences of REM suppression after stroke.
This hypothesis might also contribute to explain the results obtained, but further experiments using this experimental model are needed in order to establish its validity.
Using this experimental model, no significant difference was observed between cells knocked-down for CHC or cells expressing control siRNA (Figure 1D, upper panel).
Using this experimental model, we found that even one dose of Lactobacillus spp. in newborn chicks accelerated weight gain and resulted in significant differences in body weight.
Using this experimental model, silica induced rapid (with in minutes) and persistent (identified 14 and 28 d after a single intratracheal instillation) activation of NF-κB in the lung and that TNFα receptors greatly contribute to this activation.
Using this experimental model, we determined the importance of parasite load and MHC-II restricted CD4+ T cells for the maturation and expansion of highly cytotoxic CD8+ T cells.
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We used this experimental model to study the interactions between CL and other highly purified proteins.
Using this experimental data to model the segregation and replication of mtDNA between dividing cell in the germ line, we showed that the mtDNA copy numbers that we measured could cause a genetic bottleneck which explains the genotypic variance seen in the offspring of 246 offspring from 22 litters born to mothers with different levels of NZB/C57Bl.6J heteroplasmy.
In this study, we showed that the PDRN used in this experimental model was able to induce bone regeneration when combined to the DDM.
The dose of sumatriptan used in this experimental model is in the range of effective analgesic doses [21] and is 20 times higher than that shown to revert hyperalgesia [24] (Table 1).
An inspiratory oxygen content of 6% is the lowest possible level that can be used for this experimental model, as lower levels result in cardiac arrhythmia and cardiac failure.
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