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Using this endpoint, we observed that FOCUS had the highest levels of overall repair capacity, with HepG2, Huh7 and HepG2 2.2.15 cells having intermediate capacities.
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Thus, we devised a trial using this endpoint (ACF) to evaluate the chemopreventive effect of EPA.
We included clinical restenosis to enable comparison with studies that used this specific endpoint as a proxy for angiographic restenosis.
This chapter provides examples of clinical trials that use the endpoint, time to progression, and discloses the advantages (and disadvantages) of using this particular parameter as an endpoint in oncology clinical trials.
As the endpoint we used CV mortality after a median follow up period of 8 years.
As clinical endpoint we used a binary outcome variable indicating if the tumour metastasized or not.
In the first step we collect knowledge relevant to the target endpoint using several sources and we break down this knowledge into a collection of hypotheses.
We introduced our result by using an endpoint result for multifunctions, due to Amini-Harandi [36].
We obtained a qualitatively similar result using the endpoint of baseline FEV1/FVC ratio, although the relationship was not statistically significant.
In this respect, we use an endpoint result for multifunctions due to Amini-Harandi, [36].
For this purpose, we use an endpoint result for multifunctions which has been proved in 2010 by Amini-Harandi (Nonlinear Anal. 72 132-134, 2010).
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CEO of Professional Science Editing for Scientists @ prosciediting.com