Using the unified segmentation procedure (Ashburner and Friston 2005) implemented in SPM5 (http://www.fil.ion.ucl.ac.uk/spm), the images were segmented into GM, WM, and cerebrospinal fluid (CSF).
This was achieved by using the unified segmentation procedure implemented in SPM8, modified to include a Hidden Markov Field model as an additional spatial constraint (see http://dbm.neuro.uni-jena.de/vbm/markov-random-fields/).
The registered, distortion-corrected images were further preprocessed by co-registration to anatomical images and normalization to MNI space using the unified segmentation normalization procedure (Ashburner and Friston, 2005).
All functional volumes were spatially realigned, un-warped, normalized to the Montreal Neurological Institute (MNI) space using the unified normalization segmentation procedure of SPM5, and smoothed with an isotropic 6-mm full width at half maximum Gaussian kernel, with resulting voxels size of 2 × 2 × 2 mm.
They were then spatially normalized to the Montreal Neurological Institute space using the unified normalization-segmentation procedure in SPM5 with a resulting voxel size of 2 × 2 × 2 mm.
All functional volumes were spatially realigned, unwarped, and normalized to the MNI space using the unified normalization-segmentation procedure [Ashburner and Friston, 2005] with resulting voxels size of 2 × 2 × 2 mm.
All functional volumes were spatially realigned, un-warped, and normalised to the MNI space using the unified normalisation-segmentation procedure, with resulting voxels size of 2 × 2 × 2 mm.
All functional volumes were spatially realigned, unwarped, normalized to Montreal Neurological Institute (MNI) space using the unified normalization-segmentation procedure of SPM5, and smoothed with an isotropic 6-mm full-width at half-maximum Gaussian kernel, with resulting voxel size of 2 × 2 × 2 mm.
Extraction procedures were performed using the Unified Bioaccessibility Method (UBM) to evaluate the bioaccessibility.
Diagnosis and procedures were coded using the unified International Classification of Disease-Beijing Clinical Modification (ICD-BJCM) also issued by BPHIC.
