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The utilities associated with each health state were estimated using the TTO technique in which respondents choose repeatedly between 1) remaining in the health state without improvement for 30 years or 2) trading a number of remaining years of life in full health for receipt of a hypothetical treatment that would restore the person to full health.
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Utilities were elicited using the TTO interview (n = 121) and the enhanced TTO interview (n = 123).
Using the TTO method, three patients valued transfusion dependence as worse than being dead.
Then, health state utilities were obtained using the TTO method, which has previously been described in detail [ 25].
In an earlier study, the application of a basic mathematical routine also revealed deviating response behavior in health-state valuations elicited with the TTO technique [ 36].
The UK value set was developed using the preference elicitation technique Time Trade Off (TTO), and ranges from 1 (for the 'best' health state described with no problems on each dimension (11111))–0.594 (for the worse health state with extreme problems (33333)).
The main valuation survey was undertaken using the time trade-off (TTO) technique where individuals are asked to undertake conventional TTO valuations for a sample of health states.
The EQ-5D valued using the UK TTO value set is preferred by NICE [ 1].
EQ-5D responses were translated into EQ-5D index utilities using the UK TTO tariff [ 18].
We performed univariate and multivariable analyses using the RS, TTO, SG and WTP as dependent variables.
We measured preferences for current health using the VAS, SG, TTO, and WTP in a population of patients with cerebral aneurysms.
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