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The purpose of this study was to define and validate health states experienced by adults with relapsed or refractory B-precursor ALL in the UK and to assign utility values to these health states, from the perspective of the UK general public, using the TTO methodology.
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Researchers using the TTO need to be aware of these effects when comparing their results with related literature using the TTO.
We have measured the electrical resistivity and thermal conductivity of CeNi, LaNi and La0.15Ce0.85Ni in the temperature range 4 400 K simultaneously on the same specimen using the TTO option in PPMS (Quantum Design) facility.
Utilities were elicited using the TTO interview (n = 121) and the enhanced TTO interview (n = 123).
Using the TTO method, three patients valued transfusion dependence as worse than being dead.
Then, health state utilities were obtained using the TTO method, which has previously been described in detail [ 25].
The first two stages aimed to describe appropriate health states for further investigation via the TTO methodology used in stage 3. Prior to commencing the study, diabetologists with experience with the TTO methodology were identified and invited to form an expert steering group (ESG) to advise at all stages of the study.
Complications were identified using the AHRQ Hospital-level PSI methodology.
For this study we chose to use TTO methodology that complies with standard welfare economic principles that individuals are the best judges of their own welfare.
The EQ-5D valued using the UK TTO value set is preferred by NICE [ 1].
EQ-5D responses were translated into EQ-5D index utilities using the UK TTO tariff [ 18].
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