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Preferences have been elicited either using the TTO method with patients or a surrogate group [4, 5, 36, 44, 45, 48 50] or SG [7, 8, 13, 20, 35].
After completing the introductory ranking task, health state utilities were obtained using the TTO method.
Using the TTO method, three patients valued transfusion dependence as worse than being dead.
Then, health state utilities were obtained using the TTO method, which has previously been described in detail [ 25].
After each participant ranked the health states in order of preference, health state utilities were obtained using the TTO method.
Utility values were elicited via face-to-face interviews using the TTO method with members of the general public in each country.
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Four studies [ 61, 62, 67, 68] using a cross-sectional study design used either the TTO method or the SG method in adults with type I diabetes mellitus.
Utility values associated with the SVR state were strongly influenced by the method of assessment used and were typically highest using the TTO (ranging from 0.88 0.89) and standard gamble methods (0.86) (Table 6) and lowest using the SF-6D (0.71) and visual analog scale methods (0.74).
Utilities were elicited using the TTO interview (n = 121) and the enhanced TTO interview (n = 123).
The TTO method was selected for use in the subsequent main study because it was relatively easy for participants to understand and complete, and because it is consistent with the methods used in many recent utility valuation studies, including the MVH study [ 48, 49].
In this study, classic TTO and novel specifications of the TTO method were compared to explore the impact of the specifications of the task on health-state values.
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