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Data were normalized using quantile normalization and genes differentially expressed over time were identified using the statistical methodology SAM [ 25].
Data were normalized using quantile normalization and genes differentially expressed over time were identified using the statistical methodology SAM [ 24]. 58 genes were selected among the most differentially expressed across the time course (Table S3) and used as input of the modelling procedure.
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The frequencies of expected haplotypes were estimated by using the statistical methodologies implemented by HPlus software [ 21], which infers haplotypes based on expectation-maximization with a modified progressive ligation computational algorithm.
We used the statistical methodology prescribed by AHRQ (2012) to incorporate the complex survey design and use appropriate weights to generate national counts of ED episodes.
As a further limitation of studies of LV remodelling in relation to CRT, none has used the statistical methodology of internal and external validation.
The study was conducted using the statistical respond surface methodology.
Prodigiosin production of 7.07 g/L was achieved when the concentrations of two trace compounds, FeSO4·4H2O and MnSO4·4H2O, were optimized using the statistical experimental design methodology.
The waste cyanobacterial biomass immobilized in calcium alginate was used as a biosorbent and the process variables were optimized for maximum dye removal using the statistical response surface methodology (RS M.
DNA binding peaks were identified by using the statistical model and methodology described at (http://chipanalysis.genomecenter.ucdavis.edu/cgi-bin/tamalpais.cgi) (Bieda et al. 2006) using stringent parameters for peak identification (98th percentile threshold and p < 0.0001).
Using the statistical approach (response surface methodology (RS M) the optimum values of these most influential parameters were as follows: sunflower oil (1%), glucose (0.8%), peptone (0.8%), agitation rate (200 rpm) and incubation period (96 h) at 37 °C.
In order to standardize the production for a scale up process, the parameters necessary for interesterification had been optimized using the statistical tool, Central Composite Design – Response Surface Methodology.
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