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Organ dysfunction/failure was evaluated using the SOFA score (dysfunction = subscore ≤2, failure = subscore ≥3).
Acute renal failure and other organ failures were defined using the SOFA score [12].
Multiple previous studies have, however, reported using the SOFA score, both in isolation [31 35] and in combination with other parameters [36, 37], for outcome prediction.
The assessment of organ failure by using the SOFA score was recently proposed by the SEPSIS-3 consensus to identify high risk patients with suspected infection [15].
Patients and methods Prospective study of all Zika-associated GBS in patients admitted in our ICU from 1/12/2015 to 5/25/2016 and presenting at least one organ failure using the SOFA score.
Patient outcome was further stratified using the SOFA score.
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The model uses the SOFA score to represent severity of illness, and the model can match on either the total score (in which case the score must match exactly) or on the components of the score, which are central nervous system, respiratory, circulatory scores and the maximum of liver, renal, and coagulation scores.
Other published studies have shown promising results for predicting outcome in patients with cirrhosis using the SOFA and MELD scoring tools, and have also demonstrated that the current CTP score is not the most effective tool for predicting outcome in patients with cirrhosis [ 12, 13].
Non-neurologic organ dysfunction was measured using the SOFA and MODS scoring systems.
Unlike the MODS score in which the first value of each day is used, for the SOFA score, the worst value on each day is recorded.
Moreover, although the assumed Glasgow coma score is supposed to be used for the SOFA score, it is possible that neurological dysfunction may have been overestimated in sedated patients.
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