Sentence examples for using the small interfering from inspiring English sources

A knock down of AIF mRNA and protein levels was carried out using the small interfering RNA (siRNA) technique.

To investigate the physiological role of RNF10 in Schwann cells, we interfered in its function by using the small interfering RNA (siRNA).

Next, we determined how to influence BMP2-induced osteoblastogenesis by knocking down IRE1a using the small interfering RNA (siRNA) approach.

Furthermore, the association between their levels and the sensitivity to 5-FU was examined using the small interfering RNA (siRNA) specific for TS and DPD.

Using the small interfering RNA (siRNA) method, we demonstrated increased growth of breast cancer cells when NHERF1 expression was knocked down [ 25].

Knockdown of PDK1 using the small interfering RNA technology in breast cancer cell line MDA-MB-231 showed an impairment in cell migration and invasion and inhibition of EGF-induced calcium mobilisation.

The shRANK-1 and -4 retroviruses were generated using the retroviral small interfering RNA (siRNA) constructs pPower-hRK-1 (hRK-1) and pPower-hRK-4 (hRK-4) prepared using standard molecular cloning techniques and were used to infect ARCaPM and LNRANKL cells for 24 h in the presence of 8 μg/ml of polybrene.

Both recombinant CyPB and CyPBR62A carried three silent mutations in their coding sequence to render their transcripts resistant to the small interfering RNA used to down-regulate endogenous CyPB.

We also used TLR2 knock-down experiments to assess the involvement of TLR2 in the pathway using small interfering RNA (siRNA) specific for TLR2.

In their study, knockdown of LRP1 using LRP1 small interfering RNA in the human glioblastoma cell line U87 led to a decrease in cell migration and invasion, which suggests that the expression level of LRP1 is associated with migration and invasion capabilities of these cancer cells.

We have shown previously that HeLa cells lack LKB1 but express both CaMKKα and CaMKKβ, although it was only when CaMKKβ was knocked down using siRNA (small interfering RNA) that the phosphorylation and activation of AMPK in response to Ca2+ ionophores was reduced [ 13].