This example of a procedure comparison, evaluated using the simulation, shows that potential risk of incus luxation or fracture during piston crimping could be reduced using a second tool simultaneously.
Results obtained using the simulation show that, while a previously proposed model of endo-PG action captures some of the salient features of this enzymes behaviour, it is not sufficient to successfully predict experimental digest patterns from pectic substrates.
Table S1: Parameter values used in the simulations shown in Figures 2 and 4. Table S2: Parameter values used in the simulations shown in Figures 5 and 6. Figure S1: Steady state perturbations.
We have changed the Runge-Kutta scheme of order 2 used for the simulations shown in the 'Numerical simulations of the McKean-Vlasov-Fokker-Planck equation' section and adopted a more accurate Runge-Kutta scheme of order 4.
Comparisons between uniaxial monotonic data and FE simulations using the model show a very good agreement.
Parameters used in the simulation shown in Figure 2D are a = 3, b = 2, and τ = 100 ms. A different set of ten undergraduate and graduate students with normal or corrected vision participated in this experiment.
The validation and computational simulations using the model show it to be computationally stable, reliable, repeatable, and useful as a crash partner for other vehicles.
50 The clinical data used for comparison to the simulations showed more than a 100-fold range for clarithromycin and the values for isoniazid (CV >200%) highlight the difficulty in obtaining reproducible data with techniques such as bronchoalveolar lavage.
The simulations performed using the model show that both linagliptin 5 mg and sitagliptin 100 mg reduce HbA1c levels by 0.81% (placebo-adjusted), at week 24, when administered to patients with T2DM for 24 weeks (figure 4A,B).
All these options can be explored using the simulation; the one shown in Fig. 6 is selected here because it gives a reasonable account of observed data.
