Using the scoring model Metazoa, the genome of C. elegans was searched for potentially novel miRNA hairpins.
The scores from the SF-36 can be converted to utilities and hence to QALY's by using the scoring model as developed by Brazier J et al.[ 44] The study protocol conforms to the Helskinki Declaration and to local legislation.
Using the scoring model, this set of predictors is easy to calculate in the clinical setting and may facilitate appropriate referrals for enhanced imaging by outpatient physicians, as well as management of high-risk patients by radiologists and inpatient physicians.
Proportions (95% CI) were calculated using the Wilson score model by the OpenEpi statistical program (version 3.01), which is available online [ 23].
Using the GRACE score model, together with the determination of additional factors (congestive heart failure, PVD, prior stroke, and smoking status), we developed an improved model (KemScore) for death risk stratification for a 12-month period.
Using the summary score model, incidences of NODAT in low-risk, medium-risk, and high-risk groups in the initial cohort were 12, 29, and 56%, and in the validation cohort incidences were 11, 29, and 51%.
L ranges between 0 and 1 and represents the likelihood of a hairpin sequence to be a true miRNA hairpin given the underlying descriptors used in the scoring model.
Given 6 items, N = 1200, and 10 genetic variants explaining 1% of the variance each in one dimension of a two-dimensional trait, the probability to detect 6 or more of these variants would be >.95 under the true latent factor model, and <.20 when using the sum-score model (with the exact probability depending on the correlation between the factors).
