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Second, we examined LOH and CN alterations using the same SNP array platform, while other studies used SNPs for LOH and CGH arrays for CN analyses.
As shown in Figure 3, at BTN3A2, using the same SNP selection criterion of pairwise LD (r2>0.8), the major haplotypes within the block were delineated (Panel B).
As unfortunately we did not include the parental lines for genotyping with the segregating populations, an expected polymorphism rate could be inferred for the tested populations from large-scale genotyping trials that have been done at CIMMYT using the same SNP chip.
The program Structure (Hubisz et al. 2009) was used to analyze the population structure, using the same SNP data.
Based on these results, they suggested that using the same SNP is necessary when comparing the selection signatures among studies.
The cowpea physical map has been anchored to the consensus genetic map using the same SNP genotyping platform and sequenced BAC clones [ 13].
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In the last few years, several calling algorithms have been developed to identify CNVs at the whole genome scale using the same SNP-chips used to perform GWAS.
For example, we have found significant association with schizophrenia and the PIK4CA gene in 22q11.2DS (29) using the same SNPs as those found to be associated in a general population sample of schizophrenia (30).
More fundamentally, we show that replicated maps constructed using the same SNPs reveal new insight into bird karyotype evolution; in particular a hitherto undetected degree of fine scale heterochiasmy that opens up an exciting new opportunity to study the evolution and fitness consequences of heterochiasmy.
Secondly, it is necessary to use the same SNP when comparing the signatures of selection from one study to another.
We genotyped glass eels from 8 sampling locations across the geographic distribution of the species, using the same set of SNPs analyzed by Gagnaire et al. [ 26] in American eel.
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