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Unfortunately, a lot of different test protocols were applied making even studies hard to compare using the same endpoints.
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The concept implicitly assumes that all single substance toxicity data are recorded for the same species, in the same bioassay and using the same endpoint.
Comparison with observational data using the same endpoint suggests that the intervention using communication of risk by post with counselling by telephone was effective in increasing the numbers of 24 hour quit attempts.
On this basis, we used the same endpoint for the rest of the scaffoldins.
Thus, phase I studies of these treatments can be carried out using the same study population and endpoints as those for cytotoxic anticancer agents in addition to the assessment of immune responses.
Secondary endpoints will be analyzed using the same model as the primary endpoint, with the continuous baseline values of the endpoint being investigated included as an additional covariate.
We evaluated pairs of studies performed with different perfluoroalkane acids in the same species using the same design and found that endpoints for perfluorooctanesulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorobutanesulfonate (PFBS), and perfluorodecanoic acid (PFDA) could be discordant.
We now report the first description of bovine mammary progenitors and stem cells defined by functional growth endpoints using the same in vitro and in vivo xenotransplant systems previously developed for their human counterparts.
The mean difference (MD) was used as the effect measure where all studies reported the endpoint using the same units or scale.
A Bayesian analysis of the primary endpoint (using the same covariates as the original mixed- model analysis) provided the posterior probability distribution of the treatment difference of each treatment against placebo, i.e. the distribution of the true treatment difference given the data observed in the study.
Continuous secondary efficacy endpoints were tested for significance using the same models as used for the primary endpoint.
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