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Accordingly, we chose to knockdown AMPK α2 expression using the RNAi approach.
The silencing effects that were obtained using the RNAi approach showed more promising results in terms of prolinamide reduction on the recombinant mAb.
Additionally, using the RNAi approach, the Cre-loxP conditional and Tet-inducible systems can be used to spatiotemporally and reversibly suppress gene activity in vivo.
To further test the specificity of the link between EMT and ABC transporter expression, we analyzed the effect of downregulating EMT-inducing transcription factors using the RNAi approach.
Using the RNAi approach, we show that loss of ATOH8 in the lateral somites at the trunk level results in a blockage of differentiation and thus causes cells to be maintained in a predetermined state.
In this study, large-scale RNA sequencing (RNA-seq) was conducted to establish a transcriptome profile of six developmental stages of T. absoluta, enabling the identification of potential gene targets for knockdown using the RNAi approach.
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In order to assess the role of NCX1 we used the RNAi approach to specifically silence its expression.
Next, we explored the need for STAT3 protein in PAX3 upregulation after FGF2 stimulation using the RNAi knockdown approach.
The descriptive study of silkworm ABCG genes lays a foundation for future analysis of their physiological function and hormonal regulation, using both the RNAi approach [ 13, 14] and the binary GAL4/UAS transgenic system [ 37- 39].
We also used the RNAi-mediated approach to specifically silence NCX1 expressioNCX1
The RNAi approach has been widely used for drug development and several phase I and II clinical trials are under way.
More suggestions(15)
using the rnai design
using the rnai vector
using the rnai mechanism
using the rnai knockdown
using the rnai culture
using the Leeds approach
using the Book approach
using the rnai strain
using the Delaunay approach
using the rnai purification
using the CaDA approach
using the rnai technology
using the rnai clone
using the rnai RNAi
using the Coexistence approach
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