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The methodological quality of each included study was independently assessed by the two reviewers using the Quadas instrument (see Supplementary Appendix 2), a widely accepted and validated tool for the quality assessment of diagnostic accuracy studies in systematic reviews (Whiting et al, 2003).
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We found that the majority of studies had an exploratory design and as such showed a rather poor reporting and low quality as scored by the Quadas instrument for assessing methodological quality of individual studies in diagnostic reviews.
Exclusion of all studies with low-quality scores on the Quadas instrument would have interfered with our main objective to obtain a complete overview of markers, and was therefore not performed.
You are using the wrong instrument in the wrong venue.
The contact angle was determined using the default instrument software.
using the embedded instrument software.
DNA RNA complexes were captured using the Agilent Bravo instrument.
using the P.A.L.M MicroBeam instrument.
Data were analyzed using the instrument software.
Make loops using the 13-instrument keyboard.
Concerts are given using the instruments (call 203‐436‐4935).
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