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First an additive polygenic model was used to obtain individual environmental residuals using the polygenic function of the GenABEL library to disentangle the cryptic population structure caused by the presence of closely related animals in the sample set [39].
Heritability of meat quality traits was estimated using the polygenic function of GenABEL v1.7 [ 31].
Heritability was estimated using the polygenic function of the R package GenABEL [ 19].
Variance explained was calculated using the polygenic function with marginal SNPs or SNP pairs fitted as fixed effects.
Heritability was estimated based on a kinship matrix calculated from the 60 K SNP genotype data and using the polygenic function.
GWAS was carried out in R using the package GenABEL [ 21] running several models using the polygenic function correcting only for kinship or for kinship and population structure using either one, two, three, five or ten PCAs.
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For the calculations we use the polygenic function of R package GenABEL [39], [42], [43], [44].
Using the polygenic and mmscore functions available in GenABEL we tested the additive effect of the minor allele (T) for this SNP on the transformed plasma Aß phenotypes including covariates for age and sex in the model.
The estimation of polygenic model was performed using the polygenic option in GenABEL [ 32].
Using the polygenic approach we identified two traits with evidence for association with mitochondrial genetic variation.
The mixed linear model implemented in the polygenic function of GenABEL was used to calculate the variance explained by the SNPs with an association P value more significant than α (P ≤ 0.05) for the trait glucose and all traits measured for the ARVC pathway.
More suggestions(15)
using the ode15s function
using the 'ns function
using the optim function
using the multitask function
using the hypergeometric function
using the gologit2 function
using the svd function
using the lumiT function
using the 'flag function
using the upload function
using the rarefy function
using the fft function
using the integral function
using the glm function
using the sciatic function
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