The method, so-called the multi-moment constrained finite volume (MCV) method, uses the point values defined within single cell at equally spaced points as the model variables (or unknowns).
To evaluate the impact of individual model assumptions, univariate sensitivity analyses were performed on projected prevalence reductions at 15 years with a treatment rate of 10 per 1,000 PWID annually using the point parameter values in Table1.
We propose two ways of selection of the discrete kernel function values: using the exact point values or using the center-averaged values.
High order reconstructions are conducted cell-wisely by making use of the point values as the unknowns distributed within each triangular cell element.
Another approach consists in computing directly the distribution function on a grid by following the characteristics backward in time for one time step and interpolating the value at the feet of the characteristics using the grid point values of the distribution function at the previous time step.
Tests for linear trend were obtained by using the mid point values for each category and treating this scored variable as continuous.
By using the cut point value of SSI=8.8%, we determined seven Ags tumours (gs: SSI ⩽8.8%, Figure 1B) and 14 Agu specimens (gu: SSI>8.8%, Figure 1D) among the invasive A carcinomas.
First, we describe the à-la-Harten AMR framework: the adaptation process selects a hierarchical set of grids with different resolutions depending on the features of the integrand function, using as criteria the point value prediction via interpolation from coarser meshes, and the appearance of large gradients.
The point values used for this purpose are based on experience; usually pawns are considered worth one point, knights and bishops about three points each, rooks about five points (the value difference between a rook and a bishop or knight being known as the exchange), and queens about nine points.
The point values used for the 2013 calculations (RR = 0.55 for <12 months of ART and RR = 0.33 for ≥12 months of ART) sit towards the upper and lower end of the range found in the review (95% range for RR = 0.29 0.56).
We used the cut point value of SSI=8.8% (Kronenwett et al, 2004) to differentiate between all lesions showing significantly scattered DNA histograms (SSI>8.8%) and those with insignificantly scattered ones (SSI⩽8.8%).
