Sentence examples for using the pivotal from inspiring English sources

Approximate confidence intervals for the treatment mean difference and the individual means are constructed using the pivotal method of Woodroofe, and an approximation to the bias of the maximum likelihood estimator of the treatment mean difference is studied based on the work of Whitehead.

10 In order to ensure comparability, it was expected that the authors would apply the same procedure for SUN, using the pivotal trial 11 and the first-line outcomes from the SUN expanded-access-study, 26, 27 but only the pivotal trial outcomes were used for SUN.

If the author pooled a pivotal trial (Escudier et al, 2007) and an investigator-initiated trial (Rini et al, 2008) for BEV+IFN, the same approach should have been applied for SUN using the pivotal trial (Motzer et al, 2007) and first-line outcomes from the expanded access study (Gore et al, 2007).

We argue that a valid indirect comparison of PFS should only use the pivotal trial data, performed under the same conditions and providing the same quality of data (independent radiology review of PFS from controlled, blinded studies that are not comparable to open-label studies).

Thus, the more skeptical one is based on the prior information, the harder it is to conclude efficacy using the same pivotal trial data.

In this algorithm, we do not use codebook, and the base station generates a unitary beamforming vector set using Gram-Schmidt orthgonalization using the beamforming vector for the pivotal user.

As the conclusion, profound awareness of the benefits of using the IBS system is pivotal, as this technique is able to function effectively in the competition-based construction industry today.

Offering practical support with regard to using the RCD is also of pivotal importance when it comes to helping the GDP and the dental team in the diagnosis and documentation [ 12].

SVR12 is currently the most common endpoint used in clinical trials of novel HCV treatments, and was the assessment used in the pivotal trials involving both 3D and SOF/LDV.

Although the definitions used in the pivotal trials of trastuzumab were less restrictive [ 81– 84], a substantial minority of the Panellists preferred to use 30% intense and complete staining as a threshold for recommendation of anti-HER2 therapy.

Hence our approach focused on the comparison of the pivotal Phase III trials, using the highest data quality, in order to ensure comparability of therapy outcomes.