Therefore, several reports have recommended that preoperative estimation of PPH severity by using cardiac catheterization is necessary for the patient selection and preoperative treatment of patients with moderate PPH using vasodilators [1, 5, 18].
Only one used the term "patient selection criteria".
Physicians must continue to monitor for long-term adverse events such as chronic immunosuppression, which may lead to increased risks of infection and malignancy. 2 It is also important to consider the high cost of biologic agents and the patient selection criteria used thus far in clinical trials and other studies.
Differences in this range between studies may reflect differences in the resolution of the array platforms used, the number of cases included, the criteria used for patient selection, and the interpretation of the relevance of the identified CNVs.
The only criteria used for patient selection included the availability of tumour tissue from primary gastric carcinoma (exclusion of mucosal cancer with the largest tumour diameter of ⩽1.5 cm) and survival data.
The difference between these themes and the section on the perceived ethical issues, is that the latter is focused on physicians' answers to a specific question during the semi-structured interviews (ie. their views about what, for them, are the important ethical issues to consider when using the GIR in patient selection within renal transplantation).
It is possible that the criteria used for patient selection may not have been appropriate for identifying the patients who would benefit most from valsartan therapy.
It remains unknown whether a signature derived from a gene expression profile, such as the one used for patient selection in this study, could better identify activation of the PI3K/AKT/mTOR pathway, in comparison to mutations or amplifications in a single point of the pathway.
The criteria used for patient selection are listed in Table 1.
The strict inclusion/exclusion criteria used in patient selection for these trials may limit the generalizability of the findings to clinical practice.
