Sentence examples for using the operational model from inspiring English sources

Antagonist potency values (pKB) were determined by using the operational model for apparent non surmountable compounds, or by applying Schild's analysis for compounds displaying surmountable profiles [41], [42].

The dose response as a function of receptor level was then simulated for each agonist using the operational model (Fig. 7).

Analysis of the concentration response data using the operational model of agonism indicated that both VEGF165 isoforms had similar affinity for VEGFR2.

Analysis of the concentration response curves using the operational model of Black and Leff (1983) for partial agonists indicated that the log KA for VEGF165b was −8.83 ± 0.13 (n = 5) and the transducer constant τ was 1.65 ± 0.23 (n = 5).

Modeling of the PAM interactions with each receptor using the operational model of allosterism revealed interesting distinctions in the ways these ligands interact with each group III receptor in the presence of different agonists.

In order to determine the degree of bias of the compounds 1 and 12, we calculated their bias factors from the data sets in Figure 2 and Figure 3A,B as well as binding affinity values (Supplementary Figure S2) using the operational model.

We have used the operational model of agonism [Eq. (1) above; Black et al., 1985; ] to determine the actual loss of MOPr function that is responsible for the levels of desensitization observed.

This section provides operational definition of the terms and variables in which the study uses at the operational model.

This research focuses on the evaluation of spatial and temporal changes in evapotranspiration (ET) following the 2011 Las Conchas Fire in New Mexico (USA) using the Operational Simplified Surface Energy Balance Model (SSEBop ET).

A comparison of model forecast accuracy using the operational rain gauge-adjusted radar rainfall input (GARR) is made against rain gauge only (RGO) input for a recent flash flood.

Analysis of the data using an operational model of drug agonism has allowed us to assess and compare the actual loss of MOPr function that underlies the tolerance that developed to both agonists.