Sentence examples for using the nimblegen method from inspiring English sources

In each sample, we called more SNPs and detected more novel SNPs from the libraries that were prepared using the Nimblegen method.

Our data further shows that SNP calls obtained from the SureSelect libraries are more reliable, but we can still call a larger number of SNPs correctly using the Nimblegen method.

For each DNA sample, the number of SNPs called was higher in the library that was prepared using the Nimblegen method than in the one prepared with the SureSelect method.

There were 17 SNPs (22%) that did not follow Mendelian inheritance when the samples had been prepared using the SureSelect method and 19 SNPs (18%) when the samples had been prepared using the Nimblegen method.

In our hands, 54% of the sequence reads aligned to the targeted region, when the sequencing libraries were prepared using the Nimblegen method and 74%, when the libraries were prepared using the SureSelect method, on average.

Based on these percentages we can calculate that if the library is prepared using the Nimblegen method, approximately 1.4-fold more over-sampling is required to obtain any given average coverage than if the library is prepared using the SureSelect method.

Microarray was carried out using the NimbleGen microarray service.

Images were extracted and processed using NimbleScan v2.4 software and analyzed using the NimbleGen commercial pipeline.

cDNA was labeled using the NimbleGen Dual-Color Labeling Kit (NimbleGen) according to manufacturer's protocol.

The probes were designed and printed by Nimblegen using the Nimblegen probe design pipeline previously published (Roche Nimblegen Probe design Fundaments 2008).

After incubation, arrays were washed using the NimbleGen Wash Buffer Kit and dried using the NimbleGen Slide Dryer.