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The advantage of using the molecular clock to determine speciation rates is that it works well for all species, whether common or rare.
Age estimates were calculated using the molecular clock rate for E. coli as an approximation (3.4×10−9 synonymous mutations/generation) and assuming 300 generations per year, as per the method employed for age estimates in Yersinia pestis [42].
Divergence time from a common ancestor was estimated by using the molecular clock calculator.
The age of the proposed transfer was estimated using the molecular clock equation (t = Ks/2r).
These tests are fully equipped to decipher interspecific rate changes using the molecular clock as a null hypothesis.
Using the molecular clock of 1.3 × 10−8 substitution/site/year, we estimated that the two subspecies progenitors diverged between 0.6 and 0.25 Ma.
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We could also use the molecular clock to estimate the time of divergence of H. naledi to the other hominins.
The main reason is that geneticists use the molecular clock theory to infer the time to the most recent common ancestor (TMRCA) of each set of haplotypes clustered together (i.e., each haplogroup) in the molecular phylogenies obtained for uniparentally inherited mtDNA and Y chromosome genetic markers.
In addition, we used the molecular clock to calculate the mean age of multiple tip haplotypes, which form star-like phylogenies in the tree.
The first method uses the molecular clock.
As fossil calibration points are not available for H. commersoni s.l., we expanded the taxonomic sampling used in the molecular clock analysis to allow the use of fossil calibration points.
More suggestions(15)
using the internal clock
using the Georgian clock
using the molecular method
using the molecular stretch
using the molecular docking
using the molecular replacement
using the single clock
using the molecular diameter
using the molecular light
using the molecular descriptor
using the molecular hybridization
using the epigenetic clock
using the molecular simulation
using the molecular layer
using the molecular mass
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